Self renewal: 10 hard facts πŸ™Œ

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1. The human body in which each of us lives is made up of around 37 trillion cells, to be precise. And every day, about 1-2 percent of the cells are renewing. So, exactly after 90–100 days, a new “me” appears. We remain so busy with our routine lives that we hardly acknowledge this fact, and many of us are not even aware of it. So, β€˜change’ is the constant tune, not just within the universe but also within us.

2. Now that we understand that our bodies undergo transformation on a daily basis, So, the question is: how does this self-renewal occur? Let’s go back to our past a little bit. The human body develops from the human embryo, which is fertilized by an oocyte and a sperm cell. This embryo is made up of stem cells. The stem cells are the basic cells (undifferenciated cells) of the human body, which, through the process of mutation and transformation grow into different cells like nerve cells, bone cells, muscle cells, blood cells and so on. Throughout our lifespan, these stem cells undergo cell division and keep replicating; that’s how self-renewal happens.

3. Under normal physiological self-renewal processes, different cells in the body have differing rates of cell division. So, the replication process of various tissues, organs, and blood cells in the body has a different time frame, like the skin epidermal cells, which can take around 10–30 days, whereas a bone cell takes 3 months, or a hair grows about 1 cm in one month, and so on.

4. Though our body is constantly changing due to the continuous self-renewal process through different cell cycles like shedding the old skin cells, renewal of intestinal cell lining, and growing hair or nails on a routine basis, this isn’t a simpler process. The human body is still very complicated and has exceptions. Some cells, such as those in the brain (cerebral cortex), eyes (such as lenses), and heart, do not change from birth to death.

5. But then, why is self-renewal important and must be maintained? Under normal physiological conditions, stem cells have two functions: proliferation and differentiation. Though stem cells have a natural proliferative capacity throughout our lives, disease conditions can affect their physiological self-renewal ability and behavior due to factors such as damage or an unhealthy lifestyle (obesity, lack of physical activity, smoking, or a poor diet).

6. A lack of an appropriate environment within the body or poor maintenance of the human body might eventually lead to the exhaustion of the capacity of stem cell proliferation, which causes premature aging or tissue atrophy. With aging, stem cell activity, tissue regenerative and haemeostasis is significantly declined.

7. Sometime, due to the unhealthy environment within the body, mutations lead to aggressive stem cell division without going through the natural cell differentiation process. This can lead to abnormal tissue growth or cancer in the body. Therefore, the physiological process of stem cell division and the natural stem cell behavior can be affected by four disease conditions, like degenerative, metabolic, cardiovascular, and inflammatory conditions.

8. Regenerative medicine and therapies have arisen as a result of the discovery that defective self-renewal mechanisms in the body are the root cause of malignancies and abnormal cell proliferation. Many disorders are being treated with regenerative medicines based on stem cells. Recent years have seen a significant increase in the use of stem cell treatment to treat a variety of diseases like cancer and disorders including type 1 diabetes, heart disease, stroke, Parkinson’s, burns, osteoarthritis, by regenerating cells, repairing tissues, and transplanting organs.

9. The fact about regenerative medicine is that, though it has helped many patients around the world, the cost of treatment is quite high as the procedure is complicated and the failure rate is high. Human stem cell treatment requires culturing human stem cells in a laboratory setting for a longer period of time, which is quite difficult.

10. The market is flooded with products that promote cell regeneration, anti-aging, and longevity. The lofty claims made by these items are still quite dubious. But it is true that some supplements do work to improve health, lower inflammation, and increase immunity. But in the end, having a healthy diet, getting enough sleep, a calm mind, and exercising regularly is all that’s necessary for good health.

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Peace and love πŸ™

Merry Christmas and a Prosperous New Year 2021πŸŽ„πŸŽŠπŸŽ‰

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Wishing you and yours, Merry Christmas and a Prosperous New Year 2021.

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High Sensitive Person ( HSP): A closer look 🧐

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Being one of them or maybe, we must have come across people who are overwhelmed with trivial things, or sensory subtleties like a crowded place, loud noises, a strong odour. Or people who get easily stressed out, quickly get hurt or being overly emotional. This happens because such people are born with a particular personality trait and a susceptible nervous system so considered as High Sensitive People.

6 points to understand a high sensitive person:

1. People born with this personality trait is not abnormal, nor this isn’t a disorder. They have this personality because their brain is wired differently. There are scientific reasons for this kind of behaviour. Anatomically, their brain has a prominent insula which is responsible for their heightened state of emotional and sensory sensitivities. Their brain is wired to have a lower threshold for emotional and sensory reactivity. Genetically, they are associated with the 5HTLPR gene, which is related to mental issues like depression and anxiety. This personality trait is also known as sensory processing sensitivity (SPS).


2.High sensitive person does not necessarily are introverts. A few percentages of people with this trait can behave like an extrovert. Introverts are people who like or enjoy being alone. In contrast, HSP can have deep human connections and can be comfortable with a few set of people. They are sensitive to physical, mental, emotional and sensitive subtleties.


3.High sensitive People are deep thinkers, highly emotional and intense. They are sensitive to the external sensory sensitivities like a crowded place, parties, loud noises, strong smell or any physical sensations. Such personality is gifted with highly creative talents like art, painting, music, writing or in any such creative fields.

4.People with this trait can overthink easily. Overthinking can lead to repeating the same trail of thoughts, which can quickly turn to negative thinking. Repeating the same spiralling thought pattern can also lead to anxiety, depression and stress disorder.

5.High Sensitive people are not comfortable with multi-tasking or highly competitive environment. Too many tasks at a time can make them overwhelmed and stressful. So, choosing a profession or a job, which they can enjoy doing is quite crucial.

6.If you are born with this trait, self-acceptance is crucial. Self-criticism doesn’t hold any purpose. Though it is quite challenging to go through the everyday stress of life, living with emotional and sensory subtleties, but they have the capabilities to overcome them. They can thrive and become very successful too. Adjusting the environment according to their convenience and keeping a few trusted friends and family for emotional support is hugely beneficial. As far as physical and emotional strain is concerned, adopting a healthy lifestyle, enjoying a hobby, a daily exercise routine, sleep, mindfulness, meditation can help to lead a balanced life.

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Self confidence ✊

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Self confidence…..

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Wordless Wednesday πŸ™Œ

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Random clicks taken by me on Autumnal vibes.

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Silent Saturday πŸ™Œ

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Some random clicks of mine….

 

 

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Coconut oil🌴

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Benefits and healing properties against diseases like :

 

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Silent Sunday 🌞

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Price of fear πŸ˜’

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Fear quotes …..

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