Melatonin, commonly known as the sleep hormone is responsible for our cicardian rythm. But, it has some fascinating facts to be known.
1. The pineal gland, located at the base of the brain, is known to produce 5% of the total quantity of melatonin. Surprisingly, in all of the cells throughout the entire body, the mitochondria generate the remaining 95% of melatonin.
2. Our body cells’ mitochondria typically serve as the energy-generating organelles. They absorb glucose and oxygen to create water and ATP, which serve as the body’s power source. Free radicals are created during this procedure. However, the free radicals can be neutralised by our body’s defence systems. Melatonin acts as the potent anti-oxidant which causes free radical damage.
3. The melatonin which is produced in the body cells due to the sunlight, especially the infra red rays trigger the release of glutathione and other potent anti-oxidants. Melatonin also has anti -inflammatory properties and anti cancer properties too.
4. Since, melatonin is an effective anti-oxidant, it helps to prevent eye and ear damage. Research shows that it is effective in prevention of age related macular degeneration and retinopathy.
5. Melatonin protects the brain. Melatonin serves to promote the growth of new brain cells and improves memory, according to studies. Melatonin levels were discovered to be low in those with Alzeihmers disease. Thus, it is possible to prevent Parkinson’s and Alzheimer’s disease from becoming severely disabling by increasing melatonin levels.
6. Research shows that melatonin stimulate growth hormone production. Evidences showed that oral administration of melatonin increased the level of growth hormone, two fold times.
7.Melatonin production declines noticeably as we get older. Therefore, in order to maintain melatonin levels in our everyday lives, we must get enough sun exposure during the day and turn off lights at night so that darkness can help to stimulate melatonin production.
8. Sub-cellular melatonin which is produced in the body naturally is more effective than taking melatonin pills. Melatonin pills do work on short term basis and should be taken only if clinically recommended.
9. Aside from the infrared radiation that comes from sunlight, which is typically present in the early morning, other sources of infrared radiation that contribute to a sufficient amount of melatonin production include candlelight and being in front of a fire.
10. Incadescent light bulbs, spending time in greenery parks, outdoors all help to boost melatonin production.
1. The human body in which each of us lives is made up of around 37 trillion cells, to be precise. And every day, about 1-2 percent of the cells are renewing. So, exactly after 90–100 days, a new “me” appears. We remain so busy with our routine lives that we hardly acknowledge this fact, and many of us are not even aware of it. So, ‘change’ is the constant tune, not just within the universe but also within us.
2. Now that we understand that our bodies undergo transformation on a daily basis, So, the question is: how does this self-renewal occur? Let’s go back to our past a little bit. The human body develops from the human embryo, which is fertilized by an oocyte and a sperm cell. This embryo is made up of stem cells. The stem cells are the basic cells (undifferenciated cells) of the human body, which, through the process of mutation and transformation grow into different cells like nerve cells, bone cells, muscle cells, blood cells and so on. Throughout our lifespan, these stem cells undergo cell division and keep replicating; that’s how self-renewal happens.
3. Under normal physiological self-renewal processes, different cells in the body have differing rates of cell division. So, the replication process of various tissues, organs, and blood cells in the body has a different time frame, like the skin epidermal cells, which can take around 10–30 days, whereas a bone cell takes 3 months, or a hair grows about 1 cm in one month, and so on.
4. Though our body is constantly changing due to the continuous self-renewal process through different cell cycles like shedding the old skin cells, renewal of intestinal cell lining, and growing hair or nails on a routine basis, this isn’t a simpler process. The human body is still very complicated and has exceptions. Some cells, such as those in the brain (cerebral cortex), eyes (such as lenses), and heart, do not change from birth to death.
5. But then, why is self-renewal important and must be maintained? Under normal physiological conditions, stem cells have two functions: proliferation and differentiation. Though stem cells have a natural proliferative capacity throughout our lives, disease conditions can affect their physiological self-renewal ability and behavior due to factors such as damage or an unhealthy lifestyle (obesity, lack of physical activity, smoking, or a poor diet).
6. A lack of an appropriate environment within the body or poor maintenance of the human body might eventually lead to the exhaustion of the capacity of stem cell proliferation, which causes premature aging or tissue atrophy. With aging, stem cell activity, tissue regenerative and haemeostasis is significantly declined.
7. Sometime, due to the unhealthy environment within the body, mutations lead to aggressive stem cell division without going through the natural cell differentiation process. This can lead to abnormal tissue growth or cancer in the body. Therefore, the physiological process of stem cell division and the natural stem cell behavior can be affected by four disease conditions, like degenerative, metabolic, cardiovascular, and inflammatory conditions.
8. Regenerative medicine and therapies have arisen as a result of the discovery that defective self-renewal mechanisms in the body are the root cause of malignancies and abnormal cell proliferation. Many disorders are being treated with regenerative medicines based on stem cells. Recent years have seen a significant increase in the use of stem cell treatment to treat a variety of diseases like cancer and disorders including type 1 diabetes, heart disease, stroke, Parkinson’s, burns, osteoarthritis, by regenerating cells, repairing tissues, and transplanting organs.
9. The fact about regenerative medicine is that, though it has helped many patients around the world, the cost of treatment is quite high as the procedure is complicated and the failure rate is high. Human stem cell treatment requires culturing human stem cells in a laboratory setting for a longer period of time, which is quite difficult.
10. The market is flooded with products that promote cell regeneration, anti-aging, and longevity. The lofty claims made by these items are still quite dubious. But it is true that some supplements do work to improve health, lower inflammation, and increase immunity. But in the end, having a healthy diet, getting enough sleep, a calm mind, and exercising regularly is all that’s necessary for good health.
Everybody in this world has a deep longing for love and affection. From the new born to the older adult, everybody yearns the sense of belonging, love and compassion. Social acceptance, being valued, and recognition is longed for by one and all in the human community. Infact, we all deserve our inherent birthright of being loved, happiness, vitality, freedom, fearless and growth. So, then, from where does the negativity arise? A child being born is always happy and cheerful. It is the environment, caregivers, parents, teachers, elders, peers, and the competetive nature of this material world that pushes the child towards negativity, egoistic, pain, fear and unhappiness. These growing years, his interaction with the people around him, the environment that slowly programmed his subconscious mind with doubts, anxiety, worries, sadness, lacks and unhappiness. So, like you and me, every individual has grown up with our share of fear, limitations, and inadequacy.
Trapped emotions impact on physical health…
Within this paradigm of limitation and inadequacy in our subconscious mind, we move forward with the life journey. We are then, bombarded with challenges of day-to-day stress, relationship stress, work pressure, financial strain, and other constraints that affect our emotional health even more. Maybe, bad experiences, conflict with parents, loss of a closed one, heartbreak, deep trauma due to a failure, a toxic boss, rejection, and anger can all be overwhelming and add to our emotional baggage. We may think that emotions come and go. We can get over it, quickly or healed after some time. But, the truth is, certain emotions are’nt so superficial. Infact, it has a lasting impact on both our physical and mental health. Studies have shown that certain intense emotions get trapped in particular organs of our body. Like, anger gets trapped in the liver, while hurt, fear get trapped in the heart and so on. Ancient Ayurvedic science which is 5000 years old has rightly pointed out that too much of trapped emotions like anger, worry, chronic stress can create too much heat (Pitta) in the body which may affect the hameostasis and start creating physical illness. So, the emotional component is critical in the overall wellbeing. In reality, it is the emotional health and wellbeing that transcend physical health. Hence, the term disease means (dis-ease, absence of ease).
Evid Based Complement Alternat Med. 2017; 2017: 7618419.
Fundamentally, our mind and body are designed to be in a state of growth, restore, repair and relax. Yes, in times of potential threat and danger, the body reacts to the survival mode of fight and flight response. But, then as evolutionary, the body naturally comes back to its state of homeostasis when the threat is gone. The parasympathetic mode’s natural restoration mechanism is greatly affected by the daily’s state of chronic stress, being on the run, and always being overwhelmed. Moreover, this everyday struggle within our emotional health of mental barriers, mindset, limitations, fears, and worries added to day-to-day stress. So, leading a healthy lifestyle and caring about physical fitness has not stopped people from falling sick. People follow the best possible diet, take their best supplements, and follow an exercise routine, yet they fall into various illnesses like chronic diseases, mental issues and autoimmune diseases. Now, it has become very crucial to consider emotional health, a priority before everthing else. Maybe, this is the most critical component in our path of mental, physical, spiritual wellbeing and being a successful person we all longed to be.
It is vital to slow down... It is essential to annalyse our emotional and mental state daily, introspect at times, and slow down to understand what affects us the most. It is crucial to change the way we think, elevate our vibration, be in the positive mind space and overcome the mental barrier if we want to take charge of our mental and physical heath and wellbeing. As, for all of us, it is much easier said than done. But, indeed, we have to put some efforts on our own to make our life the way we want it to be. To take control of our physical and mental wellbeing and be in a happy, comfortable space that we all longed for.
Some ways that we can work towards for self-improvement: 1. Self-acceptance:Being aware and acceptance is an essential and fundamental change. Any circumstances, any issue or conflict that we are facing, in terms of physical or mental health, needs self-acceptance. Self-resisting, self-denial, result in more stress, conflict, and high cortisol release, which makes us unfavourable to heal or change. So, self-acceptance and being self-aware is an essential step towards change. It is necessary to accept, share with a closed one or a therapist and let go the emotional baggage. Sharing with somebody or writing down the emotions and thoughts helps us acknowledge them better and give ourselves time and space to change. Meditation and mindfullness practices also helps us in emotional growth.
2. Victimhood:Instead of living in victimhood mentality, or self-blaming, starting to explore ways and methods to be part of the healing process. Suppose, somebody is being affected by a physical or mental issue must be an integral part of the healing process. Taking responsibility and works towards healing instead of surrendering yourself fully in caregivers’ hands. It is crucial to actively partcipate in the healing process.
3. Self-compassion and patience:It is vital to approach onself with self-compassion. Being compassionate towards self, putting oneself in the right frame of mind dramatically counts. Because failing or falling is the very essence of human nature. Having faith in the Higher Power and a lot of patience is beneficial in the healing process. Because, like good times, adverse times, doesn’t last long too.
Being one of them or maybe, we must have come across people who are overwhelmed with trivial things, or sensory subtleties like a crowded place, loud noises, a strong odour. Or people who get easily stressed out, quickly get hurt or being overly emotional. This happens because such people are born with a particular personality trait and a susceptible nervous system so considered as High Sensitive People.
6 points to understand a high sensitive person:
1. People born with this personality trait is not abnormal, nor this isn’t a disorder. They have this personality because their brain is wired differently. There are scientific reasons for this kind of behaviour. Anatomically, their brain has a prominent insula which is responsible for their heightened state of emotional and sensory sensitivities. Their brain is wired to have a lower threshold for emotional and sensory reactivity. Genetically, they are associated withthe 5HTLPR gene, which is related to mental issues like depression and anxiety. This personality trait is also known as sensory processing sensitivity (SPS).
2.High sensitive person does not necessarily are introverts. A few percentages of people with this trait can behave like an extrovert. Introverts are people who like or enjoy being alone. In contrast, HSP can have deep human connections and can be comfortable with a few set of people. They are sensitive to physical, mental, emotional and sensitive subtleties.
3.High sensitive People are deep thinkers, highly emotional and intense. They are sensitive to the external sensory sensitivities like a crowded place, parties, loud noises, strong smell or any physical sensations. Such personality is gifted with highly creative talents like art, painting, music, writing or in any such creative fields.
4.People with this trait can overthink easily. Overthinking can lead to repeating the same trail of thoughts, which can quickly turn to negative thinking. Repeating the same spiralling thought pattern can also lead to anxiety, depression and stress disorder.
5.High Sensitive peopleare not comfortable with multi-tasking or highly competitive environment. Too many tasks at a time can make them overwhelmed and stressful. So, choosing a profession or a job, which they can enjoy doing is quite crucial.
6.If you are born with this trait, self-acceptance is crucial. Self-criticism doesn’t hold any purpose. Though it is quite challenging to go through the everyday stress of life, living with emotional and sensory subtleties, but they have the capabilities to overcome them. They can thrive and become very successful too. Adjusting the environment according to their convenience and keeping a few trusted friends and family for emotional support is hugely beneficial. As far as physical and emotional strain is concerned, adopting a healthy lifestyle, enjoying a hobby, a daily exercise routine, sleep, mindfulness, meditation can help to lead a balanced life.
The liver is the second largest organ in the body and has more than 400 functions. It is the primary organ of filtration, which mainly helps in the metabolism of food and absorb the necessary nutrients. It eliminates the toxins from our body daily and purifies the blood. So, it is an essential organ of detoxification for our body. Some critical functions to highlight:
1.It produces bile which helps the fat to break down during the process of digestion. 2.It helps in the production of haemoglobin from its iron storage ( liver stores iron) 3.It convert excess glucose into glycogen. 4.It cleanses the blood from toxins and poisonous substances. 5.During breakdown of protein, urea and poisonous ammonia is produced. The liver helps to eliminate them through the kidneys.
However, even if we have a powerful detoxifying organ, it gets sick and tired if we do not care enough. If we frequently consume refined, processed food, sugary items. To multiply this load, frequent intake of alcohol, smoking, drugs causes a greater danger. Also not to forget the environmental toxins, pollutants, heavy metals, pesticides from food, toxins from home cleaning products, cosmetics, perfume, the liver is unable to take the load at some points.
Signs of lousy liver functioning:
1.Tiredness 2.Collected fat around the belly. 3.Oily skin 4.Pale yellow fingernails 5.Oily skin, acne 6.Allergies 7.Digestive issues 8.Irregular bowel 9.Brain fog, headache 10 Pain on the right side of the abdomen.
Methods to detoxify the liver: 1.Eliminate the toxic sources as much as possible: We need to cut down the processed, canned, and sugary food. The refined, vegetable oil which is unhealthy fats, should be eliminated from the diet too. It is essential to minimize the use of toxic household cleaning products, cosmetics, perfumes as much as possible. As far as practically feasible, relocating from the polluted area is advisable.
2.Again it is essential to limit smoking, alcohol, drugs as much as possible.
3.Fasting: It is a crucial tool to rest the liver and minimize its load. Fasting accentuates the detoxifying process, stimulate autophagy and strengthen the immune system.
4.Focussing more on whole foods and organic vegetables, fruits given by Mother Nature than the packaged, canned food with preservatives.
5.Drinking lot of water every day will help to flush out toxins. Water added with lemon or a tinge of vinegar is beneficial. 6. Letting out toxic emotions like anger, frustration, resentment, and fear by mindful, spiritual and relaxing techniques.
7.Getting a goodnight sleep helps in the detoxification process.
8. Consuming foods which can restore the microbiome flora like fermented foods, prebiotics and probiotics. Essential foods like cruciferous vegetables, iron-rich food like spinach, beets are all useful.
Milk thistle
9. Herbs like dandelion, milk thistle, cilantro, thyme, turmeric, garlic and green tea proves beneficial.
1.You have a bodyweight within the range of average weight, according to the height and not being overweight. 2.You have a routine, regular bowel habit. 3.You have clean and clear skin. 4.You get up fresh and remain energetic. There is an absence of laziness. 5.Experiencing a sense of hunger once or twice a day. 6.You don’t have general body ache except with injury or heavy exercise. 7. You experience a sense of wellbeing and generate positive thoughts. 8. You experience deep sleep at night.
These are general signs that indicate that your body is functioning optimally and your immunity is intact. Our body’s immunity and vitality is not acquired by having a glass of smoothy, or daily going to the gym and having a load of supplements. It is the result of what you eat, how you think and how you live.
Three simple ways to build up a strong immunity is:
1.Fasting: Fasting is the simplest and easiest way of building your immunity. Ideally,15 to 16 hours of fasting every day are good enough. It is also the easiest way of losing weight. Having everyday dinner at around 6-7 PM, and not having any meal or snacks in between except water. Then, followed by having breakfast, the next morning around 10 to 11 AM gives you fasting of at least 16 hours quickly.
2. Food:Having food which is as much as close to Mother Nature. Fruits and vegetables, in their natural form or cooking minimum to restore their nutritional value. Preferable having a one-grain meal a day like brown rice or whole wheat and having meals (1-2 times /per day) with enriched portions of fibres, healthy saturated fat, protein and carbohydrate. It is necessary for avoiding processed, refined food altogether. Limiting the intake of beverages, alcohol and having more water, instead is ideal.
3. Mind and body care: Exercising every day is a must. Instead of heavy workouts in the gym, simple exercises like walking in nature, running, jogging are ideal. Physical activity throughout the day is good enough to give you a good night sleep. It is essential to maintain a positive attitude and a calm mind, to keep stress at bay. So, meditation, yoga, mindfulness practices, spiritual practices helps to build a positive and healthy mind.
Chronic Fatigue Syndrome: It is a disorder, relatively unknown to the public and even to the medical fraternity. It is a progressive, multi-system functional disorder involving the Neurological, Immune, Endocrine and digestive systems. As more and more cases are emerging, the diagnosis has now been established. This condition is also known as Myalgia Encephalomyelitis or systemic exertion intolerance disease (SEID). The syndrome slowly progresses to functional impairment. It can affect any age group, even in children. But mostly, common in women, more than men in the age group of 40-60 years.
Symptoms: Different individual is affected with different range of severity. 1.Extreme fatigue even after long hours of rest. 2.Progressive loss of stamina, both physically and mentally. 3.Loss of concentration 4.Loss of memory 5.Headache 6.Sensitivity to food, odours, chemicals 7.Unexplained joint pain. 8.Sleep disorders 9.Enlarged lymph nodes in the neck or the armpits.
Causes:The exact cause is yet unknown. But, in more and more case studies, certain contributing factors are being identified:
1.Viral infections: Like Rubella, Epstein Barr, Human herpes, Ross River viral infection can precipitate such a condition. 2.Bacterial infection like Chlamydia Pneumonia 3.Genetic Predisposition 4.Mental issues like childhood trauma, emotional trauma, stress 5.Hormonal imbalance.
Diagnosis: The diagnosis is difficult to confirm as the condition has symptoms similar to many other conditions. To make a diagnosis, doctors mainly rely on a thorough medical history, and different tests are being done to rule out other conditions. Some individual with this condition has been found to have an inadequate response to immune cells like T cells and have autoantibodies in the blood. Tests like laboratory tests, exercise tests, sleep study are done to exclude other conditions.
Management: There is as such no cure. The aim of managing such cases is to relief the individual from the symptoms.
1. Eliminate food sensitivity like common allergens nuts (peanuts, tree nuts), shellfish, gluten (wheat, rye, barley), dairy. Avoiding such food may sometimes work towards improving the symptoms.
2. Exercise and Yoga is recommended to improve physical mobility. 3. Mindfulness session to improve sleep issue. 4. Acupuncture to improve pain.
5. Improve diet and Supplementation with vitamin B complex, potassium, magnesium.
6. Bone Broth as a collagen booster
7. Meditation, nature walk to improve mental health, reduce stress and peace of mind. 8.Social support: Support from loved ones and friends is vital.
Thinking is what makes us the most intelligent species on this planet. It is this thinking what drives us to learn, study, analyze. Thinking makes us competent and innovative and help us to perform a task or job. But, when thinking becomes out of control, nagging and overtime, then, we start creating problems for us. As a habit, overthinking is not uncommon. We all may have it to some degree, more or less. Some realize it and correct it while others may be so drawn to it, which may lead to toxic consequences like anxiety, depression, suicidal tendencies and insomnia.
Ten simple ways to stop overthinking on a day to day basis:
1.Awareness: Before you can change the habit or develop a strategy, it is essential first to be aware of this habit of your mind. Whenever a thought lingers you, there is also some emotion attached to the thought. You start imagining worst possible scenario because the mind tends to think about the negative first. Maybe, this is from the time of evolution of our species, to foresee a potential danger first. So, imagination causes the mind to be strained and anxious. An anxious mind keeps brooding again and again. So, being aware of this state of mind is a fundamental key to change.
2.Reshaping your thought process: Instead of avoiding the thought or running away from it, start to reshape your thinking to a positive one. Instead of imagining the worst scenario, imagine the best scene. Instead of brooding onto the fear, create a strategy and achievable goals.
3.Change your Perspective: This is important because overthinking is ground to fear of losing or failure. So, instead of thinking on the negative terms, start thinking on the time frame—prioritize the perspective. Whether the thought or emotion do hold any value in your future, maybe five years from now or perhaps just next month.
4.Distracting the mind constructively: Many people tend to overthink when they are alone or lonely. So, it is essential to do things or develop hobbies to keep your mind occupied and let out the emotions like painting, dancing, photography, gardening, playing an instrument or even jolting down the thoughts.
5.Perfection: Aiming to be perfect is just not done. This will lead to unnecessary anxiety or stress. Instead, focussing on your progress and growing day by day is the more practical approach.
6.Overcome fear: Fear comes with failure in the past or with a bad experience in the past. But, having a past loss, doesn’t mean you will have the same outcome every time. 7.Realize the truth: The truth is that we cannot predict the future. Future is associated with an element of uncertainty. So, instead of thinking and worrying about the end, it is wiser to focus on the present moment. Focus on all the positive aspects of your life, which makes you joy and cheerful.
8.Accept your worthiness: Overthinking is usually associated with fear of failure, that you are not good enough, not worthy of success. Keep yourself reminding that you are good enough; you are capable enough to accomplish all your goals. 9.Be grateful: Living in gratitude is the most important view in life. We should never forget to be thankful for the life we lead, being able to breathe and for the things and loved ones we have around.
10 Last but not least, the physical body affects the mind and vice versa.So, regular exercise, meditation, walking in nature all help profoundly to keep a healthy mind with a healthy body.
Seratonin is a neurotransmitter, secreted in the gut and the brain. It plays a massive role in our state of wellbeing.It is responsible for giving us a feeling of a happy state of mind, a sense of satisfaction, relief from pain and control our impulses. It helps to co-ordinate the autonomic, motor, cognitive functions, appetite, emotions and feelings. It also controls our circadian rythm, which is the awake sleep cycle as a precursor of melatonin.
Seratonin cycle:
Tryptophan — 5 Hydroxytryphtophan —-Serotonin—- N -Acetylserotonin—Melatonin
When serotonin is low, it may give rise to several problems in our overall wellbeing. Before diving into the symptoms, it is essential to know what causes to reduce the level of serotonin in the body:
Causes of Low Serotonin : 1.Sedentary Lifestyle 2.Inadequate sleep. 3.Chronic Brain inflammation 4.Leaky gut syndrome 5.Poor blood sugar control 6.Magnesium deficiency 7.Omega 3 fatty acid deficiency. 8.Vitamin deficiency, namely Vitamin D, B1, B2, B6 and folate.
The different symptoms when the serotonin level is low: 1.Anxiety and Panic attacks 2.Social phobia 3.Mood swings 4.Depression 5.Low self-esteem 6.Overtly sensitive,having a sense of guilt, regrets 7.Trouble sleeping 8.Obsessive behaviour like controlling, impulsive, neat freak.
The serotonin level can be measured by Urine biomarker test (Organic Acid test).
The natural ways to improve the level of serotonin are:
1. Reducing the intake of carbohydrate, especially with a high glycaemic index like sugar, processed food. Also, switching the diet to a moderate amount of carbohydrate with a low glycaemic index like brown rice, whole grains. 2.Exercise increases the tryptophan level and balances the serotonin and dopamine balance. 3. Get better quality of sleep every day by following a routine. Make sure to get up and sleep at the same time daily to keep the awake sleep cycle intact.
4.Exposure to sunlight so the UV light absorbed in the skin can simulate Vitamin D production, which in turn stimulates serotonin production. That is why, in winters, many people suffer from depression and mood swings due to lack of exposure to sunlight. 5.Meditation helps to maintain the serotonin dopamine balance and the calmness of mind. 6.Getting a cold shower of 2-3 minutes will also stimulate the serotonin receptors. So, after a cold shower, people tend to feel relaxed. 7.Getting a body massage also helps to stimulate serotonin receptors.
8. Seratonin boosting foods: Wild-caught fatty fishes, green tea, turmeric, fermented foods, nuts, seeds, low glycaemic fruits and veggies, dark chocolate.
Milk thistle
