Self renewal: 10 hard facts 🙌

Hello everyone 🖖

1. The human body in which each of us lives is made up of around 37 trillion cells, to be precise. And every day, about 1-2 percent of the cells are renewing. So, exactly after 90–100 days, a new “me” appears. We remain so busy with our routine lives that we hardly acknowledge this fact, and many of us are not even aware of it. So, ‘change’ is the constant tune, not just within the universe but also within us.

2. Now that we understand that our bodies undergo transformation on a daily basis, So, the question is: how does this self-renewal occur? Let’s go back to our past a little bit. The human body develops from the human embryo, which is fertilized by an oocyte and a sperm cell. This embryo is made up of stem cells. The stem cells are the basic cells (undifferenciated cells) of the human body, which, through the process of mutation and transformation grow into different cells like nerve cells, bone cells, muscle cells, blood cells and so on. Throughout our lifespan, these stem cells undergo cell division and keep replicating; that’s how self-renewal happens.

3. Under normal physiological self-renewal processes, different cells in the body have differing rates of cell division. So, the replication process of various tissues, organs, and blood cells in the body has a different time frame, like the skin epidermal cells, which can take around 10–30 days, whereas a bone cell takes 3 months, or a hair grows about 1 cm in one month, and so on.

4. Though our body is constantly changing due to the continuous self-renewal process through different cell cycles like shedding the old skin cells, renewal of intestinal cell lining, and growing hair or nails on a routine basis, this isn’t a simpler process. The human body is still very complicated and has exceptions. Some cells, such as those in the brain (cerebral cortex), eyes (such as lenses), and heart, do not change from birth to death.

5. But then, why is self-renewal important and must be maintained? Under normal physiological conditions, stem cells have two functions: proliferation and differentiation. Though stem cells have a natural proliferative capacity throughout our lives, disease conditions can affect their physiological self-renewal ability and behavior due to factors such as damage or an unhealthy lifestyle (obesity, lack of physical activity, smoking, or a poor diet).

6. A lack of an appropriate environment within the body or poor maintenance of the human body might eventually lead to the exhaustion of the capacity of stem cell proliferation, which causes premature aging or tissue atrophy. With aging, stem cell activity, tissue regenerative and haemeostasis is significantly declined.

7. Sometime, due to the unhealthy environment within the body, mutations lead to aggressive stem cell division without going through the natural cell differentiation process. This can lead to abnormal tissue growth or cancer in the body. Therefore, the physiological process of stem cell division and the natural stem cell behavior can be affected by four disease conditions, like degenerative, metabolic, cardiovascular, and inflammatory conditions.

8. Regenerative medicine and therapies have arisen as a result of the discovery that defective self-renewal mechanisms in the body are the root cause of malignancies and abnormal cell proliferation. Many disorders are being treated with regenerative medicines based on stem cells. Recent years have seen a significant increase in the use of stem cell treatment to treat a variety of diseases like cancer and disorders including type 1 diabetes, heart disease, stroke, Parkinson’s, burns, osteoarthritis, by regenerating cells, repairing tissues, and transplanting organs.

9. The fact about regenerative medicine is that, though it has helped many patients around the world, the cost of treatment is quite high as the procedure is complicated and the failure rate is high. Human stem cell treatment requires culturing human stem cells in a laboratory setting for a longer period of time, which is quite difficult.

10. The market is flooded with products that promote cell regeneration, anti-aging, and longevity. The lofty claims made by these items are still quite dubious. But it is true that some supplements do work to improve health, lower inflammation, and increase immunity. But in the end, having a healthy diet, getting enough sleep, a calm mind, and exercising regularly is all that’s necessary for good health.

Thanks for reading.

Peace and love 🙏

3 facts of Hyperhidrosis 😰

Hello everyone ! Have a wonderful and great day 🙋🏻

3 things to know about hyperhidrosis :

1. Hyperhidrosis is a condition characterised by excessive sweating from the eccrine glands, which is about 4-5 times more than an average person sweating. This condition can harm the life of the individual at the professional, mental and social level. Physiologically, sweating is a normal phenomenon which occurs to regulate the body’s temperature. It is actually, a function of the sympathetic nervous system that causes the sweating. In hyperhidrosis, tremendous sweating occurs in hands, feet, scalp, face and armpits, making it annoying and irritable. This condition affects about 5% of the global population.

2. Hyperhidrosis has no known cause but can be associated with certain medical conditions. So, reasons can be group as :
a.Idiopathic (no known cause)
b.Hereditary factor
c.It can be related to certain medical underlying conditions and due to the intake of certain medications.
d.Specific conditions which can be associated with hyperhidrosis: Obesity, Stress disorders, chronic anxiety, hyperthyroidism and menopause.

3. There is no known cure for hyperhidrosis. Though topical creme and antiperspirant are there, treatments are available to manage such cases quite well. Some treatment options are :
a.Iontophoresis: It is a non-invasive procedure of delivering electric current to the affected body parts like hands, feet or armpit while that particular body part is submerged in water. Though this procedure is common, it has a limited success rate and requires frequent intervention.
b.Botox injections: This method is quite effective but again requires numerous injections and repeated sessions.
c.Sympathectomy: This is a minimal surgical procedure which is used to remove the sympathetic nerves that control the sweating of the affected parts. This procedure is the most effective one.
The cost-effectiveness of each of the procedures can be decided, depending upon the individual’s requirement and severity.

Thanks for reading.

Blessings and much love to all 💐

 

11 ways to get rid of Acid reflux 😠

Hello everyone ! Have a wonderful and safe day 🙋🏻

Reflux is the upward movement of the material from the stomach to the oesophagus through the lower oesophageal sphincter. The content of the material can be acid, food or air now and then. Usually, the sphincter remains tight, but when it becomes loose, stomach content migrates to the oesophagus.

Common causes of Acid reflux can be:

1.Overweight or obese.
2.Pregnancy
3.Hiatus Hernia (when part of the stomach bulges out into the chest through the diaphragm)
4.Eating a heavy meal and lying down on the right side or bending forward.


5.Drinking fizzy, carbonated drinks or alcohol.
6.Smoking.


7.Having too many beverages, like tea and coffee.
8.Intake of blood pressure medication or pain killers.

Commonly occurring symptoms are :

Burning sensation behind the sternum/breast bone. Also known as heartburn.
Belching/ Regurgitation of food.
Acidic taste in the mouth.
Atypical symptoms like coughing at night.

Acid reflux pain or heartburn can be very annoying and uncomfortable. If the episodes become frequent, the diagnosis is called gastroesophageal reflux disease (GERD). The condition is diagnosed based on physical symptoms. But in prolonged cases, or frequent episodes, or in case of hiatus hernia, oesophageal stricture, diagnosis is done by ultrasound and CT scan. The treatment recommended with medication proton pump inhibitors, Omeprazole. In severe cases, some may require surgery.

But, there are several Lifestyle measures which we can adapt to reduce Acid reflux:

1. Changing the eating pattern by avoiding eating late at night. Avoiding large, heavy meal.

2. Getting rid of trigger foods like spicy, fried, citrous or even tomato-based food items.

3. Eating small meals at regular intervals and eating slowly by chewing properly.

4. Avoiding carbonated and fizzy drinks, avoiding alcohol, too much tea and coffee.

5. Quitting Smoking.

6. Destressing yourself before meals like by taking 5-6 deep breaths before each meal.

7. Don’t eat 2-3 hours before going to bed.

8. Sleeping on the left side so that it decreases the pressure on the lower oesophageal sphincter and reduces gastric stress.

9. Using a pillow of sufficient height to support the head so that the abdomen and oesophagus are all in alignment.

10. Avoid tight clothing which may again cause gastric pressure and on the oesophageal sphincter.

11. Food preferred are


Green leafy vegetables
Non-citrous fruits
Oatmeal
Eggs
Lean meat and fish
Probiotics like yoghurt, buttermilk
Fennel seeds
Winter melon/Ash gourd
Ginger/turmeric


Aloe vera
Healthy fats like avocado, walnut.

Thanks for reading.

Blessings and much love to all 💐

 

 

 

 

 

Insulin Resistence : 6 ways to reverse naturally 🙌

Hello everyone ! Have a wonderful weekend 🙋🏻

Why is insulin so important? Insulin is the hormone which is secreted by the pancreas, which regulates the blood glucose level at every single point in time. In a typical scenario, whenever, we eat a meal comprising of macronutrients carbohydrate, protein and fat, the body breakdown the carbohydrate portion instantly to provide energy. The blood glucose level gets spiked up—insulin releases which help the body cells to take up the glucose. And the remaining part is transported to the liver which is stored as glycogen. The insulin also helps to keep the protein and fat stored in the liver. By this way, insulin helps to maintain the blood glucose level in the bloodstream.

Insulin resistance is a state in the body, when the body cells do not respond to the hormone insulin, as a result of which the cells are unable to utilise the glucose in the bloodstream. So, the blood glucose level as well as the blood insulin level rises. Nowadays, insulin resistance cases are on the rise. Many patients can even remain undiagnosed. Such condition can lead to a host of problems like weight gain, obesity, high cholesterol, belly fat, high blood pressure, type 2 diabetes, polycystic ovarian syndrome and breast cancer.

Common symptoms are :

1. Hunger after eating: As the body cells are unable to take up the glucose in the blood due to unresponsiveness to insulin, the body cells remain starved despite a high level of glucose in the bloodstream. So, the person feels hungry even after having a hearty meal. Your sugar cravings are more. You tend to be craving for more carbohydrate-rich foods.
2. Frequent urination: Because the insulin is not regulating the blood sugar properly, the kidneys have to make more urine to eliminate the excess blood sugar. You have the urge to urinate more frequently.
3.Thirsty always: When you are flushing urine more frequently, you are going to be thirsty more.


4. Abdominal fat: There usually is a deposition of fat around the abdomen, waistline.
5.Swollen ankles: Insulin causes the kidneys to retain salt and water as a result of which you may notice swollen ankles.


6.Dark patches: Due to high insulin level in the bloodstream, you may see dark patches in the neck, armpit and groin.


7.Skin tags.
8.Irregular menstrual cycle: Insulin resistance state influences other hormones in the body. In the case of women, there is an imbalance in the sex hormones and result in PCOS (polycystic ovarian syndrome). A vicious cycle sets in.

A blood test can diagnose insulin resistance state, namely, the blood glucose level (the fasting and postprandial), glucose tolerance test and Glycosylated haemoglobin test.

Some natural ways to lower the blood insulin level:

1.Losing weight: We need to make efforts to lose weight by adopting an active lifestyle and a low carbohydrate diet. It will help the body to slowly breakdown the reserved fat to utilise for energy sources. We should have more high fibre vegetables (non-starchy veggies), nuts, seeds, avocados, healthy fats like omega-three fatty acids, saturated fats like coconut oil, olive oil, eggs and butter.
2. Fasting: Fasting for at least 12 -16 hours will lower the blood insulin level and the blood glucose level. It will stimulate the breakdown of the fat reserve for the energy sources.


3.Intervals: Eating in intervals with a gap of 4-6 hours in between and altogether avoiding snacking.
4. Exercises mainly, high intensity or weight training helps to increase the sensitivity of muscles towards insulin. It also stimulates the use of glucose without the help of insulin.


5. Stress reduction: Stress increases the blood cortisol level, which in turns cause a high insulin level. So reducing stress by practising mindfulness, try walking in nature, yoga and meditation. Reducing stress by letting go of anger, hatred, fear, frustration or any trapped emotions.


6. Sleep: Sleep deprivation causes excess blood glucose level, which in turn increases a high insulin level. This elevated insulin level influences the other hormonal cycles.

Some low carb vegetables and fruits that can keep the blood sugar and insulin level low:
Green leafy vegetables like spinach, lettuce, kale
Aubergine
Avocados
Cabbage
Broccoli
Cucumber
Radishes
Green beans
Cauliflower
Mushroom,
Tomatoes
Paprika


Fruits like watermelon, oranges, berries like strawberries, raspberries,

Thanks for reading.

Blessings and much love for all 💐

 

 

 

 

 

6 natural ways of Thyroid care 🙌

Hello everyone ! Have a wonderful and safe day 🙋🏻

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The thyroid gland is butterfly-shaped in the neck, which is responsible for metabolism and growth. This gland mainly secretes hormones, thyroxine and triiodothyronine. It is controlled by the pituitary gland which is called the master gland of the hormonal axis. Thyroid problems are widespread and experienced by millions, but about 60% of such cases remain undiagnosed. Thyroid problems are elevated these days because of high stress in day to day life, unhealthy food habits, sedentary lifestyle, and perhaps increase in top environmental toxins. Though thyroid problems can appear in both men and women, but women are most likely to be affected than men. Although there is no specific cause, the reason can be due to estrogen dominance, a state where the estrogen level is elevated than the progesterone level.

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Thyroid issues can be broad as
#dietary deficiency like iodine deficiency such as in case of goitre  

#autoimmune in origins like hypothyroidism called Hashimoto’s thyroiditis and hyperthyroidism called Graves disease.

#Thyroid nodules.

Symptoms depend on different conditions. Common symptoms for thyroid problems can be:
tiredness,
fast heartbeats,
fatigue,
weightloss (hyperthyroid) or weight gain (hypothyroid),
irritability,
anxiety,
heat intolerance and 
irregular menstrual cycle.
The association of thyroid issues with irregularity or imbalance in women reproductive hormones have been quite relevant. There is a significant association of thyroid issues with conditions like uterine fibroid, endometriosis, menstrual irregularities, premenstrual symptoms (PMS), polycystic ovarian syndrome (PCOS) and difficulty in menopause.

According to modern medicine, depending upon the thyroid hormone levels in the blood, physical examination, ultrasound and physical symptoms, the diagnosis is confirmed. Drugs are given as a substitute for thyroid hormones in case hypothyroidism.

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But in general, the thyroid gland can be maintained healthily by changing our food habits and lifestyle. 6 natural ways are: 
1.Food: Apple, coconut, yoghurt, beans, spinach, onions, pumpkin seeds, walnuts, mango, olive oil, garlic, mushroom, nuts, sea fishes like sardines and salmon, using natural rock salt in meals.

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2. Avoiding junk food and soya products.

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3. Daily yoga and meditation are beneficial;

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4. The message of the gland with pure cold-pressed walnut oil or red onion (antibacterial and anti-inflammatory properties) can help significantly to reduce inflammation around the organ.
5. Vitamin D, Selenium and magnesium supplementation are helpful.

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6. Detoxifying: our body is highly equipped with organs (liver, kidneys, skin, lungs) to eliminate toxins. We do not require expensive therapies or sessions or any special diet for detoxification. We, need to stick to a clean diet, plenty of fluids, proper sleep, no excess processed food, sugar and alcohol to enhance the natural detoxification process.

Thanks for reading.

Blessings and much love to all 💐

Autophagy: What is it, and how to induce it?🙌

Hello everyone! Have a wonderful and safe day 🙋🏻

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The term “autophagy” means eating thyself where “auto” is self, and “phage” is eating. The name has been there in medicine since the 19th century. But the term became quite popular among the medical community in around 2016 when Japanese researcher Dr Yoshinori Ohsumi won the Nobel Prize.

Physiologically, the term means that the body has a natural capacity to eat and clean out the debris, junk and all the unnecessary components in the cells and recycle them as newer and healthier ones for smooth functioning. It’s a form of self-preservation process that the body has an innate capacity. In this way, the toxic, inflamed cells in the body which are responsible for chronic diseases are to be recycled and self preserved to healthier cells. The ageing process slows down, the body weight can be maintained. The process is possible in case of all cells in the body, including brain cells, heart, liver, lung, kidneys and all.

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This is a natural phenomenon, which the body is capable of undergoing. But due to various factors, this bodily process isn’t so effective as it should be. The reasons are manifold like for the continuous binging of food, adopting an unhealthy lifestyle and choosing the wrong food items (high calories) to eat and so on. So, in many individuals, the process either slows down or work at a very minimal level. Therefore, there are vast dumping of debris and toxins in the cells leading to various chronic conditions like obesity, diabetes and cancers. Autophagy has received much public attention these days for its capacity to prevent diseases like cancers. But, more studies are required in this area.

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In an individual with a high carbohydrate intake of calories 300 to 500 calories/day, the process remains less effective. So, people are mainly adopting the Keto diet and lifestyle. Consuming food with healthy fats and a minimum level of carbs with increasing physical activities and short intervals of fasting induces ketosis in the body. Ketosis causes the body to use the fat reservoir for energy sources instead of carbohydrate as there is a minimum intake of sugar. Usually, the keto diet can be useful in weight loss and fat reduction, or muscle building process. Staying in ketosis can ignite the process of autophagy faster in a short interval of 12 hours.

Specific ways to ignite the process of autophagy are:

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1.Sleep: Adequate quantity of sleep daily of at least 8 hours a day is beneficial. But more than the number, the adequate quality of sleep matters. Sleep accentuates the lymphatic flow between the neurons and fastens the cleaning process of neuronal debris and plaques. So, every day you get up with a clean brain, not only helps in smooth cognitive functioning but also fewer chances of ageing disease like dementia, Alzheimer’s and Parkinson’s disease. Sleep not only promotes autophagy in the brain but also in all somatic cells, thereby cleaning toxins and debris throughout.

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2. Adopting a ketogenic diet: Not changing the diet regime drastically from high carb to low carb and high fat. Because, it may cause severe outcomes like low blood sugar, electrolyte imbalance and fatigue. Instead, keeping in mind, the body’s tolerance level, slowly making changes by lowering the intake of carbs in the diet up to 50 calories/day. Incorporating more healthy fats in the diet of 80% of the entire daily intake of at least 2000 calories/day can give good results in the body. The body slowly ignites the natural process of autophagy faster, which takes a long time with a carbohydrate-rich diet. If you want, you can get more information about adopting ketogenic diet: Click the link https://481cb43mpgt7wbgmt08k1v3k18.hop.clickbank.net/

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3.Intermittent fasting: This is itself a vast topic to discuss. It means that scheduling the meal timings in a day in between fasting intervals. The fasting period can be 8-10 hours to 14 -16 hours a day. There are some extreme methods of fasting, necessary for specific parameters to target. But for regular individuals like you and me, an early dinner or sometimes skipping a meal or fasting, a single day can be constructive. Early dinner can give us fasting of at least 10 hours every day. If you want, you can get more information on intermittent fasting : Click the link

https://ca5fc89pxgpyy9ofji3dmj4p5z.hop.clickbank.net/

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4.Exercise: Heavy intense training and practice do more harm than good. Instead, it is wise to adopt interval training, to stretch, walking, yoga is all beneficial.

Thanks for reading.

Blessings and much love💐


Post : 7 perks of having fibre food.

Fibre foods are plant extract foods which are either soluble or insoluble fibres. Fibres are found in the outer layer of whole grains and plants which remain undigested in the gut. They cannot be digested by our body’s digestive enzymes. As they remain undigested, they facilitate the digestion process, help in digesting other food in the gut and also modulate the consistency of body waste. Dietary fibre foods are whole wheat, rice, oats, corn, fruits, veggies, pulses and nuts.

Now, the 7 perks of fibre food that I would like to convey are

  1. Fibre food are ideal for weight management reason. This type of food gives the sensation of fullness after consumption and provide the bulk of body waste which helps to clean the bowel. Therefore, it helps to maintain the body weight. 
  2. As fibre food takes longer chewing time, longer digestive time, so glucose formation in body is slow, insulin response is slower too. The person tend to eat less and does not feel hungry for a long time. As a result, slowly loses the excessive weight. Therefore, these food are highly recommeded for weight loss.

3. Fibre food helps in reducing blood sugar level. Since fibre content is not digested hence it is not added to the blood sugar level. Clinically, fibre food have found to reduce postprandial glycaemia and increase insulin sensitivity. So, they are good for diabetics.

4.Since this food maintain the blood sugar level and gives the sensation of fullness, They are clinically recommended for gastrointestinal disorders and obesity.

5. Plant extracts food are rich in fibres, antioxidants, vitamins and minerals. Hence, they have the added benefits of removing toxins along with body waste and help boost the body’s immunity.

6. Studies have proved that fibre food helps in lowering blood cholesterol level so help in reducing risk of hypertension, stroke and coronary artery diseases.

7. Fibre food facilitate the digestive process, helps in removing unwanted waste, toxins, helps in cleaning the bowel. Therefore, fibre food intake helps in reducing the risk of bowel cancers.


Post: Sitting, a health hazard !

Sitting, a health hazard !

Sitting long is as hazardous as smoking. When we sit long, we use less energy and body’s metabolism slows down. This in turn give rise to a host of health concerns.

Right from evolution, the human race was never meant for a sedentary lifestyle. Humans had to work hard, struggle a lot to survive on earth. But things dramatically changed with science and technology. With each passing days, as our comfort level rises, the human behaviour and habits changed. It was more of mental work and less of physical activity. But our body’s physiology remained the same. We, humans were never meant to sit or lie down long. We were meant to stay upright. Staying upright actually helps our body’s metabolism and digestion to function appropriately. Body’s energy store is well utilised and bone strength is maintained. 

Talking about health hazards, sitting long slower the metabolism and as a result body’s over all energy utilisation is reduced. The muscles of the legs, back, abdomen loosen and relaxed. With such posture for a long time can lead to chronic body, back, leg pain. Since, the metabolism decreases, there is chances of high blood sugar, high cholesterol, increase fat store in the body. The chances of obesity, fatty liver, diabetes are all on rise. There is high risk of cardiovascular diseases and cancer contributed to mortality rate. Recent studies have found that sitting prolong for than eight hours can have the same risk of dying similar to the risk of dying from smoking and obesity.

Different researches are going on throughout the world on various recommendations of how long sitting hours and how many hours of physical activity required for different age group of people. So the exact hours and time is quite difficult to recommend. But the simple rule I follow, is trying to build a habit, an awareness, a reminder to move around, have a bit of physical activity in between interval of at least 30 mins of sitting continuously. Apart from that, there is my routine daily physical activity or exercises of at least 60 mins. Different people have different level of endurance and bodily requirements. So it is wise to choose your own convenient routine of physical activity and bodily movements. My intention of writing this post was to make you aware about the dangers of sitting long. If you feel that you are not doing enough of physical activity, it’s never too late to turn around and increase your movements. So in the process, you will enjoy the great health benefits from this simple change of habit.