Self renewal: 10 hard facts πŸ™Œ

Hello everyone πŸ––

1. The human body in which each of us lives is made up of around 37 trillion cells, to be precise. And every day, about 1-2 percent of the cells are renewing. So, exactly after 90–100 days, a new “me” appears. We remain so busy with our routine lives that we hardly acknowledge this fact, and many of us are not even aware of it. So, β€˜change’ is the constant tune, not just within the universe but also within us.

2. Now that we understand that our bodies undergo transformation on a daily basis, So, the question is: how does this self-renewal occur? Let’s go back to our past a little bit. The human body develops from the human embryo, which is fertilized by an oocyte and a sperm cell. This embryo is made up of stem cells. The stem cells are the basic cells (undifferenciated cells) of the human body, which, through the process of mutation and transformation grow into different cells like nerve cells, bone cells, muscle cells, blood cells and so on. Throughout our lifespan, these stem cells undergo cell division and keep replicating; that’s how self-renewal happens.

3. Under normal physiological self-renewal processes, different cells in the body have differing rates of cell division. So, the replication process of various tissues, organs, and blood cells in the body has a different time frame, like the skin epidermal cells, which can take around 10–30 days, whereas a bone cell takes 3 months, or a hair grows about 1 cm in one month, and so on.

4. Though our body is constantly changing due to the continuous self-renewal process through different cell cycles like shedding the old skin cells, renewal of intestinal cell lining, and growing hair or nails on a routine basis, this isn’t a simpler process. The human body is still very complicated and has exceptions. Some cells, such as those in the brain (cerebral cortex), eyes (such as lenses), and heart, do not change from birth to death.

5. But then, why is self-renewal important and must be maintained? Under normal physiological conditions, stem cells have two functions: proliferation and differentiation. Though stem cells have a natural proliferative capacity throughout our lives, disease conditions can affect their physiological self-renewal ability and behavior due to factors such as damage or an unhealthy lifestyle (obesity, lack of physical activity, smoking, or a poor diet).

6. A lack of an appropriate environment within the body or poor maintenance of the human body might eventually lead to the exhaustion of the capacity of stem cell proliferation, which causes premature aging or tissue atrophy. With aging, stem cell activity, tissue regenerative and haemeostasis is significantly declined.

7. Sometime, due to the unhealthy environment within the body, mutations lead to aggressive stem cell division without going through the natural cell differentiation process. This can lead to abnormal tissue growth or cancer in the body. Therefore, the physiological process of stem cell division and the natural stem cell behavior can be affected by four disease conditions, like degenerative, metabolic, cardiovascular, and inflammatory conditions.

8. Regenerative medicine and therapies have arisen as a result of the discovery that defective self-renewal mechanisms in the body are the root cause of malignancies and abnormal cell proliferation. Many disorders are being treated with regenerative medicines based on stem cells. Recent years have seen a significant increase in the use of stem cell treatment to treat a variety of diseases like cancer and disorders including type 1 diabetes, heart disease, stroke, Parkinson’s, burns, osteoarthritis, by regenerating cells, repairing tissues, and transplanting organs.

9. The fact about regenerative medicine is that, though it has helped many patients around the world, the cost of treatment is quite high as the procedure is complicated and the failure rate is high. Human stem cell treatment requires culturing human stem cells in a laboratory setting for a longer period of time, which is quite difficult.

10. The market is flooded with products that promote cell regeneration, anti-aging, and longevity. The lofty claims made by these items are still quite dubious. But it is true that some supplements do work to improve health, lower inflammation, and increase immunity. But in the end, having a healthy diet, getting enough sleep, a calm mind, and exercising regularly is all that’s necessary for good health.

Thanks for reading.

Peace and love πŸ™

Trapped emotions: Time to let go! πŸ™Œ

Hello everyone ! Have a wonderful and safe day πŸ™‹πŸ»

As a human being…

Everybody in this world has a deep longing for love and affection. From the new born to the older adult, everybody yearns the sense of belonging, love and compassion. Social acceptance, being valued, and recognition is longed for by one and all in the human community. Infact, we all deserve our inherent birthright of being loved, happiness, vitality, freedom, fearless and growth. So, then, from where does the negativity arise? A child being born is always happy and cheerful. It is the environment, caregivers, parents, teachers, elders, peers, and the competetive nature of this material world that pushes the child towards negativity, egoistic, pain, fear and unhappiness. These growing years, his interaction with the people around him, the environment that slowly programmed his subconscious mind with doubts, anxiety, worries, sadness, lacks and unhappiness. So, like you and me, every individual has grown up with our share of fear, limitations, and inadequacy.

Trapped emotions impact on physical health…
Within this paradigm of limitation and inadequacy in our subconscious mind, we move forward with the life journey. We are then, bombarded with challenges of day-to-day stress, relationship stress, work pressure, financial strain, and other constraints that affect our emotional health even more. Maybe, bad experiences, conflict with parents, loss of a closed one, heartbreak, deep trauma due to a failure, a toxic boss, rejection, and anger can all be overwhelming and add to our emotional baggage. We may think that emotions come and go. We can get over it, quickly or healed after some time. But, the truth is, certain emotions are’nt so superficial. Infact, it has a lasting impact on both our physical and mental health. Studies have shown that certain intense emotions get trapped in particular organs of our body. Like, anger gets trapped in the liver, while hurt, fear get trapped in the heart and so on. Ancient Ayurvedic science which is 5000 years old has rightly pointed out that too much of trapped emotions like anger, worry, chronic stress can create too much heat (Pitta) in the body which may affect the hameostasis and start creating physical illness. So, the emotional component is critical in the overall wellbeing. In reality, it is the emotional health and wellbeing that transcend physical health. Hence, the term disease means (dis-ease, absence of ease).

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Evid Based Complement Alternat Med. 2017; 2017: 7618419.

Published online 2017 Aug 22. doi: 10.1155/2017/7618419

Emotional health is crucial…

Fundamentally, our mind and body are designed to be in a state of growth, restore, repair and relax. Yes, in times of potential threat and danger, the body reacts to the survival mode of fight and flight response. But, then as evolutionary, the body naturally comes back to its state of homeostasis when the threat is gone. The parasympathetic mode’s natural restoration mechanism is greatly affected by the daily’s state of chronic stress, being on the run, and always being overwhelmed. Moreover, this everyday struggle within our emotional health of mental barriers, mindset, limitations, fears, and worries added to day-to-day stress. So, leading a healthy lifestyle and caring about physical fitness has not stopped people from falling sick. People follow the best possible diet, take their best supplements, and follow an exercise routine, yet they fall into various illnesses like chronic diseases, mental issues and autoimmune diseases. Now, it has become very crucial to consider emotional health, a priority before everthing else. Maybe, this is the most critical component in our path of mental, physical, spiritual wellbeing and being a successful person we all longed to be.

It is vital to slow down...
It is essential to annalyse our emotional and mental state daily, introspect at times, and slow down to understand what affects us the most. It is crucial to change the way we think, elevate our vibration, be in the positive mind space and overcome the mental barrier if we want to take charge of our mental and physical heath and wellbeing. As, for all of us, it is much easier said than done. But, indeed, we have to put some efforts on our own to make our life the way we want it to be. To take control of our physical and mental wellbeing and be in a happy, comfortable space that we all longed for.

Some ways that we can work towards for self-improvement:
1. Self-acceptance: Being aware and acceptance is an essential and fundamental change. Any circumstances, any issue or conflict that we are facing, in terms of physical or mental health, needs self-acceptance. Self-resisting, self-denial, result in more stress, conflict, and high cortisol release, which makes us unfavourable to heal or change. So, self-acceptance and being self-aware is an essential step towards change. It is necessary to accept, share with a closed one or a therapist and let go the emotional baggage. Sharing with somebody or writing down the emotions and thoughts helps us acknowledge them better and give ourselves time and space to change. Meditation and mindfullness practices also helps us in emotional growth.


2. Victimhood: Instead of living in victimhood mentality, or self-blaming, starting to explore ways and methods to be part of the healing process. Suppose, somebody is being affected by a physical or mental issue must be an integral part of the healing process. Taking responsibility and works towards healing instead of surrendering yourself fully in caregivers’ hands. It is crucial to actively partcipate in the healing process.


3. Self-compassion and patience: It is vital to approach onself with self-compassion. Being compassionate towards self, putting oneself in the right frame of mind dramatically counts. Because failing or falling is the very essence of human nature. Having faith in the Higher Power and a lot of patience is beneficial in the healing process. Because, like good times, adverse times, doesn’t last long too.

Thanks for reading.

Blessings and much love to all πŸ’

 

 

 

 

 

 

 

 

 

Food and mood πŸ˜‡

Hello everyone ! Have a wonderful and safe Sunday πŸ™‹πŸ»

There is an old Spanish proverb “The belly rules the mind” which is indeed true. Food, not only has a significant impact on the physical body and overall health but also on our day to day thinking, decision making, and the entire mental health as well. This saying has been prevalent among various faiths and belief systems from the ancient time. Science has proved in recent times in various researched-based studies.

According to the widely practised Yogic and Ayurvedic literature, everything that is matter arises from a fundamental source called Prakriti (meaning Mother Nature). So, the three primary Gunas (qualities) arises from Mother Nature. The three primary Gunas which are present in all objects and beings surrounding us are – Tamas, Rajas and Sattva. We, human unlike other beings or objects can choose the level of the three qualities in our individual lives and minds depending upon our choices of food, lifestyle and the kind of thoughts we like to cultivate. Our wellbeing and health mainly depend on these preferences. The three states are relative, and keep changing during our day to day life depending on our food choices and lifestyle preferences. Therefore, the three states are:

Satva: It is a state of beingness, in balance, in harmony and a favourable condition. For these qualities to nurture, we need to adapt to the food, that comes directly from Mother Nature. The food that comes from the soil and not from factories. To maintain calmness of mind, we have to adopt and practise Yoga, meditation regularly, which keep the mind stable and peaceful. Such a state is an ideal state of health and wellbeing free from diseases.

Rajas: This is the state of mind related to desires, passion, longing and attachment to worldly pleasures, excessive material goods, excessive work, excessive exercising and even extreme thinking. When we have this state of mind, there is craving for fried, spicy food and stimulants like alcohol, smoking and all sorts of other stimulants.

Tamas: This state of mind is darkness, ignorance and passive.
It is the most unproductive state of mind. Such a state mainly attracts overeating, oversleeping, passive state, fearful state. This state of mind mostly attracts fatty meat, processed and refined food.

So, the kind of food, we have on our plate, that we consume every day, or with each meal determines the state of mind, thought process, our prospects of the world, people around us. Therefore, in yogic practises, the ultimate goal is to cultivate the practice of Satva, adopt Satvic food to be close to our Creator, our beingness, our most authentic self.

Not just mentioned in ancient literature, food impact on both physical and mental health have been studied in several research-based projects all over the world in recent times. For decades, we have been surrounded by sugary, refined, processed and fatty foods, which are like impossible to avoid. Because of their easy accessibility, binging on this kind of foods has made it difficult for the body to deal with them. Apart from causing multiple physical health issues, including lifestyle diseases and obesity, they are grievous for our mental health and brain too. Researches have found out; junk foods are not only killing our health but also causes the shrinking of our brain. The primary functions of the brain being the cognitive functions, the ability to think, perform challenging tasks have found to impact the wrong kind of nutrition. Such a diet is found to have a long term effect on normal brain activities and memory. Habitual intake of such foods changes and alter the programming of the brain.

An Australian study found that not just in the adults and adolescence. Still, pregnant women, too who fed on junk foods, gave birth to children who were more aggressive, fearful, throw tantrums and has less tolerable personality. Without Omega 3 fatty acids, and other nutrients dense food, the brain does not develop naturally.Some more information on Omega three fatty acids https://healthhappinesshealing.org/wp-admin/post.php?post=3844&action=edit

So to conclude, the impact of nutrition in the overall health is wholesome. Not just the diseases but also chronic health issues like autoimmune diseases, obesity, heart diseases, rheumatoid arthritis, diabetes, cancers, celiac disease, irritable bowel syndrome, thyroid issues can be controlled and well managed by changing the diet and lifestyle. Even the impact of nutrition on mental health has been immense. So, with proper diet and lifestyle changes, depression, mood disorders and day to day cognitive functions thought process, task performance, agility, tolerance, decision-making skills could all be improved.

Thanks for reading.

Blessings and much love to all πŸ’

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Post : Truth and fiction – Coronavirus 🦠

Hello everyone πŸ™‹πŸ»β€β™€οΈ. Stay home and stay protected πŸ™

It’s the correct knowledge and information that is going to guide us during this Catastrophic situation. So, I would like to share this Gregg Braden’s video which has some valuable information. Though, this is a quite long video, but it is worth watching.

Courtesy: Greggbraden.com

Check out this link to overcome fear and stress : https://www.heartmath.com

Thanks for watching.

Blessings and much love πŸ’

Post: Do Love your genes ❀️ Make better choices!

Hello everyone! Have a great Wednesday πŸ™‹πŸ»

We have 50 to 75 trillion cells in our body. Believe it or not, each of them has a nucleus which has a DNA strand of about 6 feet. Now, how such long length of DNA strand fit inside the small nucleus of a tiny cell. The DNA strand is wrapped around a cluster of proteins called the histones. Histones are like molecular spools. These molecular spools form the chromatin, where there are the sequencing of proteins. These chromatins form the complex structure of DNA, that is the chromosomes. There are about 30 million spools in each of the cells. So just imagine, how much of genetic material, we carry in each of our cells. The functional unit of DNA are the genes encoded in it. It is this genetic codes which tell the cell how to function and who to become. That is how a muscle cell differs from a neuron or a skin cell.

A magnifying glass focussing on a section of a DNA strand.

Epigenetics meaning above the genes. So, epigenetics are chemical tags that sit on the chromatin. Some epigenetic marks can condense the chromatic making the cell unable to read the genes underlying, in other words, they turn the genes off. Again, some epigenetic marks can decondense the chromatic making the cell accessible to read the underlying genes. So, then the genes are turned on. Therefore, these epigenetic marks are responsible for influencing our cell biology. So, in our body, though each cell has the same DNA, it is these epigenetic marks which instruct the cell to turn on or off the particular genes. This is how a muscle cell or a neuron function differently from a skin cell. Now, the question is when do the epigenetic marks laid down the information or instructions to the cells. Most of it occurs during the embryonic development inside the womb. Initially, when the embryo is only a few cells big, there are very less epigenetic marks on the cells, As the days pass by, the influence of environment slowly increases the epigenetic marks on the cells.

In a pregnant lady, the growing embryo inside her womb has been influenced by the food she eats, behaviour, her stress level, habits (like smoking alcohol). That’s how the epigenetic marks are laid on the chromatin of each cell. That is how the foetus genes are affected and also the long term health effect of the child. Even as the child grows into an adult, the habits, behaviour, disease pattern does not entirely depend on the hereditary genes. Researches have shown that the environment continues influencing the epigenetic marks of the chromatins. Throughout life, the genes keep turning on and off depending on the environmental choices, pattern or the kind of environmental responses, the person perceives.

We keep making choices on the perception of this world, thoughts, emotions, lifestyle habits, eating habits, stress responses and other environmental influences. Depending on all these choices, our body’s nervous system influences the chemical pathways (neurohormonal pathways) instructing the genes through receptor responses (some genes get turn on while some get to turn off) in different cells of our body leading to different changes that occur regarding health, ageing, longevity, diseases, stress levels and wellness. Improving our choices ( being in a positive environment), positivity, reducing stress levels, healthy eating, active physical life all can affect our genes greatly. Have an impact on our overall wellbeing ,can reduce disease prospects, or can make healing faster.

So, the concept of “we” being the victims of hereditary genes doesn’t completely hold the truth. We still hold our magic stick depending upon the choices we make. We are still the “masters” of the body in terms of our health and wellness.
If you wish to know more about this topic, I recommend the book “Change your Genes, Change your life” Creating optimal health by the New Science of epigenetics. by Kenneth R. Pelletier

Thanks for reading.

Blessings and much love to all πŸ’

Post : Stillness πŸ‘€

Hello Everyone ! Happy Friday 🌼 and have a great weekend ahead πŸ™‹πŸ»

Every day, in this hustle-bustle of life, there is too much noise to ever be in silence. The cacophony of sounds distract us all the time and our mind is filled with too many overcrowded thoughts. By the end of the day, you are too exhausted physically and mentally with this craziness. But then, can this drama of the outer world ever pause? The answer is yes, unless, we allow ourselves to be paused and listen to the silence.

Yes, the essence of being silent in stillness even for a short time can be a source of great strength, highly rejuvenating not just mentally but physically too. It gives you the much-needed fuel before you step into a new day. We feel stillness is difficult behind all the distractions. Everything gets in our way. It’s only when we become aware and learn to listen to the stillness, we get time to truly rest.

The best day to practise stillness is right from today. Each morning or evening or summer or winter has its kind of stillness. Sitting or lying down, after breathing deeply with eyes closed, away from noises and trying to follow up your natural breaths for some time will let your life simply, drawn into this darkness where there is no limitations or constraints. Though it may sound simple, it isn’t that easy. But then, this is a practice. Initially, you are so caught up with thoughts that the mind slips for tomorrow’s meeting, the emails that you have to check, you have to meet up a friend, your next meal to be prepared come all your way. I know my friends, this is a little difficult, as you are trying to focus on nothing and there isn’t any goal to reach.

You start forming a habit when you are doing every day for a couple of minutes. Some days are difficult with too much clutter of thoughts while some days are easy to focus. That’s all ok, my dear friends. As the days pass by, you will learn to enjoy this silence, the peace. The darkness within this stillness has much more to say than anything else. I have tried myself and am still learning and enjoying the process. You will experience inner peace and wisdom, your spiritual growth. This is what people call as meditation or the sacred stillness is all about.

I have already talked about the science point of view ( in some of my previous posts) what meditation, stillness bring about changes in the brain and also in the physical wellbeing (reduces inflammation).
Practising stillness also helps in a better quality of sleep. So, the benefits are plenty. I am not exactly using the term “meditation” as there are several methods of guided thought meditations. Here, I am simply talking about the stillness, listening to the silence which helps to nourish us both physically and mentally. It gives us a deeper sense of connectedness, perhaps with the Divine.

Whether or not, to practise stillness or meditation is entirely our choice to make. We can start listening to silence and practise stillness or continue to hide from it.

Thanks for reading.

Blessings and much love to all πŸ’