Tag: supplements

10 interesting facts about Melatonin 😴

by drjurisharma, posted in brain, cognitive health, emotional health, eyes, Life, nature, Uncategorized

Hello everyone🖖

Melatonin, commonly known as the sleep hormone is responsible for our cicardian rythm. But, it has some fascinating facts to be known.

1. The pineal gland, located at the base of the brain, is known to produce 5% of the total quantity of melatonin. Surprisingly, in all of the cells throughout the entire body, the mitochondria generate the remaining 95% of melatonin.

2. Our body cells’ mitochondria typically serve as the energy-generating organelles. They absorb glucose and oxygen to create water and ATP, which serve as the body’s power source. Free radicals are created during this procedure. However, the free radicals can be neutralised by our body’s defence systems. Melatonin acts as the potent anti-oxidant which causes free radical damage.

3. The melatonin which is produced in the body cells due to the sunlight, especially the infra red rays trigger the release of glutathione and other potent anti-oxidants. Melatonin also has anti -inflammatory properties and anti cancer properties too.

4. Since, melatonin is an effective anti-oxidant, it helps to prevent eye and ear damage. Research shows that it is effective in prevention of age related macular degeneration and retinopathy.

5. Melatonin protects the brain. Melatonin serves to promote the growth of new brain cells and improves memory, according to studies. Melatonin levels were discovered to be low in those with Alzeihmers disease. Thus, it is possible to prevent Parkinson’s and Alzheimer’s disease from becoming severely disabling by increasing melatonin levels.

6. Research shows that melatonin stimulate growth hormone production. Evidences showed that oral administration of melatonin increased the level of growth hormone, two fold times.

7.Melatonin production declines noticeably as we get older. Therefore, in order to maintain melatonin levels in our everyday lives, we must get enough sun exposure during the day and turn off lights at night so that darkness can help to stimulate melatonin production.

8. Sub-cellular melatonin which is produced in the body naturally is more effective than taking melatonin pills. Melatonin pills do work on short term basis and should be taken only if clinically recommended.

9. Aside from the infrared radiation that comes from sunlight, which is typically present in the early morning, other sources of infrared radiation that contribute to a sufficient amount of melatonin production include candlelight and being in front of a fire.

10. Incadescent light bulbs, spending time in greenery parks, outdoors all help to boost melatonin production.

Thanks for reading.

Peace and love 🙏

Self renewal: 10 hard facts 🙌

by drjurisharma, posted in brain, emotional health, eyes, health, Life, mental health, nature, wellness

Hello everyone 🖖

1. The human body in which each of us lives is made up of around 37 trillion cells, to be precise. And every day, about 1-2 percent of the cells are renewing. So, exactly after 90–100 days, a new “me” appears. We remain so busy with our routine lives that we hardly acknowledge this fact, and many of us are not even aware of it. So, ‘change’ is the constant tune, not just within the universe but also within us.

2. Now that we understand that our bodies undergo transformation on a daily basis, So, the question is: how does this self-renewal occur? Let’s go back to our past a little bit. The human body develops from the human embryo, which is fertilized by an oocyte and a sperm cell. This embryo is made up of stem cells. The stem cells are the basic cells (undifferenciated cells) of the human body, which, through the process of mutation and transformation grow into different cells like nerve cells, bone cells, muscle cells, blood cells and so on. Throughout our lifespan, these stem cells undergo cell division and keep replicating; that’s how self-renewal happens.

3. Under normal physiological self-renewal processes, different cells in the body have differing rates of cell division. So, the replication process of various tissues, organs, and blood cells in the body has a different time frame, like the skin epidermal cells, which can take around 10–30 days, whereas a bone cell takes 3 months, or a hair grows about 1 cm in one month, and so on.

4. Though our body is constantly changing due to the continuous self-renewal process through different cell cycles like shedding the old skin cells, renewal of intestinal cell lining, and growing hair or nails on a routine basis, this isn’t a simpler process. The human body is still very complicated and has exceptions. Some cells, such as those in the brain (cerebral cortex), eyes (such as lenses), and heart, do not change from birth to death.

5. But then, why is self-renewal important and must be maintained? Under normal physiological conditions, stem cells have two functions: proliferation and differentiation. Though stem cells have a natural proliferative capacity throughout our lives, disease conditions can affect their physiological self-renewal ability and behavior due to factors such as damage or an unhealthy lifestyle (obesity, lack of physical activity, smoking, or a poor diet).

6. A lack of an appropriate environment within the body or poor maintenance of the human body might eventually lead to the exhaustion of the capacity of stem cell proliferation, which causes premature aging or tissue atrophy. With aging, stem cell activity, tissue regenerative and haemeostasis is significantly declined.

7. Sometime, due to the unhealthy environment within the body, mutations lead to aggressive stem cell division without going through the natural cell differentiation process. This can lead to abnormal tissue growth or cancer in the body. Therefore, the physiological process of stem cell division and the natural stem cell behavior can be affected by four disease conditions, like degenerative, metabolic, cardiovascular, and inflammatory conditions.

8. Regenerative medicine and therapies have arisen as a result of the discovery that defective self-renewal mechanisms in the body are the root cause of malignancies and abnormal cell proliferation. Many disorders are being treated with regenerative medicines based on stem cells. Recent years have seen a significant increase in the use of stem cell treatment to treat a variety of diseases like cancer and disorders including type 1 diabetes, heart disease, stroke, Parkinson’s, burns, osteoarthritis, by regenerating cells, repairing tissues, and transplanting organs.

9. The fact about regenerative medicine is that, though it has helped many patients around the world, the cost of treatment is quite high as the procedure is complicated and the failure rate is high. Human stem cell treatment requires culturing human stem cells in a laboratory setting for a longer period of time, which is quite difficult.

10. The market is flooded with products that promote cell regeneration, anti-aging, and longevity. The lofty claims made by these items are still quite dubious. But it is true that some supplements do work to improve health, lower inflammation, and increase immunity. But in the end, having a healthy diet, getting enough sleep, a calm mind, and exercising regularly is all that’s necessary for good health.

Thanks for reading.

Peace and love 🙏

6 important facts: Probiotics and SBO supplements 🙌

by drjurisharma, posted in brain, celebration, cognitive health, emotional health, food, healing, health, Life, Science, wellness

Hello everyone! Have a wonderful and safe day 🙋🏻

 

We know by now that our gut flora is full of the microbiome. It is this microbiome flora which maintains our health and wellbeing. Previously, nobody ever worried about this microbiome flora which is natural and responsible for our good health. But in today’s time, due to consuming highly processed, refined food, heavy toxins and pesticides in food, unhealthy lifestyle, artificial farming and hybrid products, environmental toxins, this gut microbiome flora is greatly affected. The overall health and immunity status of people have suffered much. As a result, many chronic health issues like chronic inflammation, inflammatory bowel diseases, autoimmune conditions, and cancers have increased.

In the past, food used to come directly from the soil. People lived closer to nature. Nowadays, whatever food is available in the Supermarket, are all cleaned, bleached grains, vegetables, fruits, and processed refined, packaged foods. Therefore, the gut microbiome flora is shrinking slowly. This is why more and more people are suffering from gut health issues and other chronic severe conditions.

6 Important facts about Probiotics and SBO supplements:

1. Probiotics are live organisms which are found in some natural foods. They are also available in the form of supplements. There are mainly two types: Lactobacillus acidophilus and Bifidobacteria. They have become very popular in recent times because they provide the gut microbiome flora with good bacteria, improve digestion, increase immunity, and improve overall health and wellbeing.


Probiotics are found naturally in fermented foods like:
Kefir
Saurkraut
Kombucha
Natto
Yoghurt
Apple cider vinegar
Miso
Gherkins
Kimchi

3. Dairy-based probiotics are naturally found in yoghurt, especially in goat milk yoghurt and raw cheese. But, in processed cheese and poorly storage dairy products, probiotic bacteria get denatured. Sometimes, acidic ph in the stomach also can harm the good probiotic bacteria found in dairy. So, having dairy products may not provide enough probiotic in our body.

4. SBOs are soil-based organisms found in the soil, about 6 inches below the topsoil. They are found to be very beneficial to overall good health. To name a few, like Anthrobacter Simplex, Bacillus brevis and many more. Commercially grown plants and crops lack SBOs as they are no longer grown on the natural organic environment. So, SBO supplements are very much in demand.

5. SBO supplements are useful in improving overall immunity status, improving inflammation and digestion. Patients affected by chronic issues, or who undergo chemotherapy, SBOs supplements help improve gut functions and immunity status significantly.

6. While taking Probiotics and SBO supplements, one should start slowly and in consultation with a Physician. About 70%-80% of people can show marked improvement after taking supplements like improving digestion, reducing inflammation, and improving immunity. While some may show slow progress like the symptoms can slowly reduce. While there may not be any improvement or sometimes some people, there may have a negative impact. So the response is quite variable. The decision of using such supplements depends on the individual and his or her requirement. Otherwise, regular intake of natural sources of Probiotics can be very beneficial too.

Thanks for reading.

Blessings and much love to all 💐

Enzymes: 6 amazing facts 🙌

by drjurisharma, posted in food, healing, health, Life, mental health, nature, Science, wellness

Hello everyone ! Have a wonderful and safe day. 🙋🏻

Enzymes are an integral part of the body’s metabolism, growth and repair. They are crucial for gut health, the ageing process and maintaining overall good health.

Six facts about the fantastic enzymes :

1.Enzymes are protein or protein-like substances found in our body which acts as a catalyst at a cellular level and speed up the biochemical process of energy production, growth and repair of tissues.


2.Enzymes are specific and are very selective to which substance they bind to and activate the process of breakdown and digestion. Whatever food, we consume, each of the food types stimulate a different set of enzymes.
Carbohydrate stimulates enzyme Carbohydrase like Amylase. The enzyme lactase digests lactose. People who lack lactase suffers from lactose intolerance.
Protein stimulates enzyme Protease like Pepsin, trypsin.
Lipid stimulates enzyme Lipase which digests fat by emulsification.
Some more examples of enzymes are: ATP synthase helps to convert ADP to ATP. Helicase unzips DNA strands.

3. Enzymes are sensitive to temperature and ph change. A slight temperature change can either slow down or speed up the enzyme activity. Large temperature changes can denature and can even lose their function. Similarly, ph changes can directly influence enzyme activity.

4. Enzymes stores in our body can be depleted slowly due to causes like ageing, unhealthy food habits like overprocessing, refined food consumption. Overcooking of food can cause the breakdown of natural enzymes present in the food. Therefore, enzyme deficiency in the body can lead to digestive issues like bloating, gas, food intolerance, anaemia, lethargy and heartburn.

5. There have been multiple enzyme supplements available and marketed commercially with different benefits in the market. But it is essential to know that not enough studies/researches are done to prove either their efficacy or side effects. So, before using the supplements, it is crucial to inform your Physician or else, it may have a drug interaction with your regular medicines currently taken.

6. Certain food rich with natural enzymes which can be consumed but in moderation:
Pineapple has bromolein, and Papaya has papain, and they both are protein enzymes. Avocado has Lipase, and bananas have amylase and maltase. Natural raw honey, wild sprouts (alfa, alfa) and kefir are also rich in digestive enzymes. Fermented food like saurkraut, kimchi is rich in digestive enzymes and even probiotics.

Thanks for reading.

Blessings and much love to all 💐

 

Amazing benefits of Inositol 🙌

by drjurisharma, posted in food, healing, health, Life, mental health, nature, Science, travel

Hello everyone ! Have a wonderful and safe day 🙋🏻

Inositol is a pseudovitamin, more commonly referred to as vitamin B8. Unlike other vitamins, Inositol is not considered essential as the body can make it. The kidneys and other body parts can produce it. Inositol is mostly found in the brain. It is vital for the body because it is involved in several crucial processes of the body namely –


1. Insulin regulation and helps to maintain blood sugar. It can improve the insulin sensitivity of the insulin receptors and reduces insulin resistance.
2. Fat metabolism which prevents the fat from accumulation.
3. Neurotransmitter synthesis like Seratonin which is greatly affected by Inositol. Therefore, it affects our mood and behaviour.
4. Calcium signalling.
5. Epigenetic regulation.
6. Cytosketetal formation.

Because it plays an essential role in these processes, it helps to benefits and improve many chronic conditions like :


1.Depression

2.Anxiety

3.Panic attacks, Eating disorders, Mood disorders.

4.Polycystic ovarian syndrome

5.Infertility, regulate the Menstrual cycle.

6. Inflammation

7.Acne

8.Since it helps in insulin regulation and aids in metabolism, it helps improve diseases like Diabetes type 2, autoimmune diseases and cancers.

Food sources of Inositol are Citrus fruits, cantaloupe, grains, legumes, nuts.

Supplement: Myo inositol. Supplements and doses are recommended under Physician supervision.

Thanks for reading.

Blessings and much to all 💐

Magnesium : A mineral with great benefits 🙌

by drjurisharma, posted in healing, health, Life, mental health, Science, wellness

Hello everyone. Have a beautiful and safe day 🙋🏻

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Being irritable at times, feeling less energetic, having sleep disturbances may not be familiar with me alone but with many of you as well. We blame it to our lifestyle of working up to late hours, stress, anxiety or maybe having too much tea/ coffee in the day. But, we fail to understand that this could be the reason for the deficiency of mineral-like Magnesium—an unknown epidemic which most of us are generally not acquainted. About 80% of the population suffer from magnesium deficiency, so imagine how prevalent the problem exists.

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A vital mineral as well as an electrolyte, Magnesium is used in many biochemical processes within our body. Lifestyle habits like stress, anxiety, lack of sleep, sugar intake, having carbonated drinks can deplete magnesium storage in the body. Even the soil where crops and greens are grown can be devoid of Magnesium. Therefore, many reasons contribute to magnesium deficiency issue. So, despite following a healthy diet, we may end up having a magnesium deficiency.

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Magnesium is a vital mineral used as a co-factor in many of the essential enzymatic biochemical processes. Energy production cycle called the Krebs cycle; it plays an important role. Magnesium contributes as a vasodilator, anti-inflammatory, anticoagulant. It is used in a considerable amount in the mineralisation of bones. Almost 60% of Magnesium is stored in bones, and the rest is stored in the red blood cells, kidney.
Clinically, Magnesium deficiency or Hypomagnesemia is measured by a blood test or magnesium level in urine. But, despite being such a common problem, many physicians failed to acknowledge it because of lack of enough researches or maybe it isn’t easy to measure the exact level in the body.

Some common causes of magnesium deficiency are:

1. Decreased intake: High intake of processed food and prolonged fasting.
2. Malabsorption: Irritable bowel syndrome-like Crohn’s disease, frequent laxative use and diarrhoea.
3, Certain conditions like SIADH (a condition in which the body secretes too much of antidiuretic hormone),
4, Acute pancreatitis, Burns, lactation, diabetes, excessive sweating and alcoholism.
5. Medication that causes of depletion of stored Magnesium are antibiotics, antivirals, antiepileptics,
6. Uses of Cisplatin, corticosteroids, proton pump inhibitors and diuretics.

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Some common symptoms are :
1. Muscle twitching, cramps, spasm.
2.Tiredness, dysphagia.

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3. Irregular heartbeats.
4. Migraine headache.
5. Insomnia
6. Kidney stones
7. Weight gain
8. Anxiety
9.Autoimmune diseases
10. Ringing in the ears.

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Usually, the ideal dose is about 400mg/day. The important sources can be dietary sources like Almonds, nuts, seeds, spinach, pulses.
Other methods are magnesium ionic drops, magnesium oils for body massage and supplements. Oral supplements are available in bound form like Mg oxide, citrate, glutamate, glycinate, taurate and so on. But, supplementation should be used under a physician’s supervision.

Thanks for reading.

Blessings and much love to all 💐

 

 

 

Zinc: 10 vital uses 🙌

by drjurisharma, posted in healing, health, Life, mental health, Science, wellness

Hello everyone! Have a wonderful and safe day 🙋🏻

Human population studies have shown that almost about 2 billion population suffer from Zinc deficiency in the world. Zinc is a trace mineral which is most vital for many of our body’s natural processes. It is not produced in the body but has to be supplemented by food sources and supplements.

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The body’s vital processes where zinc plays a significant role are :
1. Zinc acts as a co-factor in almost 1000 enzymes in protein synthesis.
It plays a role in cell division and DNA synthesis.

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2. It supports the immune system. Zinc reduces the oxidative stress and stimulates the particular immune cells like the mast cells which helps in fighting bacterial infections, viruses and promotes the immune response. So, it reduces the infection course in common cold. Also, because of it’s antioxidant properties, it helps in reducing inflammations in the body. In the present scenario of COVID 19 pandemic, Zinc is very effective in the prevention and management of COVID 19. Therefore, it is wise for us to daily have Zinc intake through food sources to have a strong and powerful immune system especially these days. 
3. It plays a vital role in the growth and development in-utero (during pregnancy), during childhood and adolescence. It plays a vital role in cell proliferation, metabolism. It helps in cognitive functions and learning.
4. It is essential for the proper functioning of the smell and taste senses.
5. It promotes wound healing. Because of anti-inflammatory property and its role in collagen synthesis, zinc is very essential in the healing of burns, ulcers and other skin injuries.

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6. Another important function of zinc is that it plays a very important role in neural functioning. It helps to control the brain body’s response to stress. Researches have shown that zinc supplements along with antidepressants given to depressed patients have dramatically improved symptoms.

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7. It plays an important role in skin health. It is widely distributed through the layers of the skin. Zinc acts as a transporter in the cells of the skin. Therefore, it’s deficiency causes a lot of skin problems like acne, eczema, dermatitis, rosacea, hyperpigmentation and also alopecia.
8. It is important for prostate health. Zinc concentration is highest in the prostate tissue. It helps in the synthesis of testosterone. Its deficiency can lead to hypogonadism.


9. Zinc helps in the storage of insulin in the beta cells of Pancrease. It is essential in the conversion of proinsulin to insulin. Therefore, zinc is significant in both the production and storage of insulin. Because of it’s, antioxidant properties, Zinc helps in lowering the oxidative damage caused by free radicals and reduces the effects of diabetes-induced complications. So, Zinc supplementation is very important in diabetics patients.

10. Zinc plays a vital role in the synthesis of melanin which is a protective pigment for the eyes. It helps to transport Vitamin A from the liver to the retina and helps in the production of melanin. Zinc deficiency can lead to poor or impaired vision.

So, this magical mineral has tremendous health benefits to talk about. Deficiency can lead to numerous health issues. To name a few like,

Delayed or retarded growth, various skin problems, weakened immune system, chronic diarrhoea, delayed sexual maturity, delayed healing of wounds, early ageing, poor vision and behavioural issues.

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Mineral food zinc supplements. Large medical capsule with Zinc letters and many small pills. 3d illustration.

Ideally, Zinc required for daily intake in a normal adult is 10 mg/day from food sources. Supplementation of 15-30mg/day is clinically recommended if deficient in Zinc related issues. But higher doses of daily consumption of about 60mg/day for about 10 weeks can lead to Zinc toxicity. Zinc supplementation is given in the form of Zinc acetate, Zinc sulphate, Zinc gluconate, Zinc citrate. Supplementation should be taken always under clinical supervision.

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Both plant and animal food sources of Zinc can be absorbed in the body. But, whole grains, legumes, cereals contains phytate which may inhibit the Zinc absorption in the body. This is a fact that needs to be aware of in case of a vegetarian diet. Fortified grains, cereals can be the substitute if deficiency issues arise. Other food sources of Zinc are :

Healthy product sources of zinc.
Healthy product sources of zinc. Food rich in Zn

Thanks for reading.

Blessings and much love to all 💐

 

Post : Supplements: An aid or just hype. 4 points of understanding 👐

by drjurisharma, posted in Uncategorized

Hello Everyone! Have a great weekend 🙋🏻

Whenever we visit a grocery store. There is always a separate counter for vitamins and minerals supplements. It feels like why do we have to take the pain of looking for fresh fruits and vegetables, instead take some of the supplements home which will fulfil our daily requirements of vitamins and minerals. But, it is not so. Right from evolution, humans are born to live and survive on food. So, it is always the food first.

It is the healthy diet which is the key to provide you with the best sources of vitamins and minerals to the body for growth and maintenance. If you are eating the best healthy form of diet and nutrient-dense food, then supplements are not necessary at all. But, sometimes, even if you are having a healthy diet, there are some deficit for which you are showing some signs and symptoms. Then, there is a requirement for supplements. So, vitamins and minerals pills are a supplement to your diet to recover the deficit but not replacement.

4points of understanding

1.Balanced diet: Moreover, a healthy balanced diet is not only a source of vitamins and minerals but also a good source of dietary fibres, protein, carbohydrate and fat which are essential for the body. Supplements do not contain any kind of dietary fibres so they are not wholesome as in a healthy diet. Again vitamins and mineral supplements do not get fully absorbed sometimes in the body like for instance, fat-soluble vitamins do not get absorbed if taken in empty stomach. Therefore, there is no substitute for a healthy nutritious diet. So, never rely on supplements for your daily requirement. Before, taking supplements, it is important to consult your Physician.

2.Heart diseases: People with risk of heart disease are usually advised to take Omega 3 fatty acids which are found in fishes like salmon, herring, tuna, at least twice a week (American Heart Association). So, omega 3 fatty acid supplements (EPA +DHA) are recommended for such people. It is always wise to discuss the diet plan with the Physician before consuming such supplements.


3.Antioxidant vitamin supplements (A, C and E): There is yet to be proved clinically that antioxidant supplements provide overall benefits. So, it is not to rely on these supplements for the daily dietary sources of antioxidants. Therefore, antioxidant food sources like veggies, fruits and whole grains are the best.

4.Harmful: Too much of any supplements which are not required for the body, taken in large quantity can be potentially damaging. Too much of iron can have the risk of chronic diseases, or too much vitamin A can cause to have birth defects. Again, the interaction of dietary supplements, along with prescription drugs, can sometimes be potentially toxic.

Thanks for reading.

Blessings and much love to all 💐

Post: Moringa, the new superfood. 5 proven health benefits.

by drjurisharma, posted in Uncategorized

Moringa oleifera, a native plant of Northern India, also grows in tropical regions of southern Asia, South America and Africa have been in the health trend for its tremendous health benefits. It has been there for thousands of years, as a dietary supplement. Alternative names being popular as drumstick tree, or horseradish tree or ben oil tree.

Science-based studies have proved recently that this plant, its leaves, fruits and seeds have many health benefits and can be regarded as a superfood.

Many households in India, Africa uses the fruits, seeds, leaves for cooking. Otherwise, it is available in powdered form, pills, capsules as supplements.
5 known benefits:

1.Dietary supplement: The moringa contains a variety of vitamin, protein and minerals. Vitamins mainly B1 (thiamine) B2 (riboflavin), B3 (niacin) and B6. It contains Vitamin C and folate. Loads of minerals like magnesium, phosphorus, calcium, iron and zinc. It has no harmful cholesterol. Moringa seeds are rich in antioxidant properties and so help in protecting skin and hair.

2.Helps in weight loss: Research shows that moringa extract helps in weight loss. It’s high vitamin B content facilitate digestion. It lowers cholesterol and helps the digestion of fat and prevent storing of fat. It has anti-inflammatory properties. It lowers cholesterol, due to compounds like isothiocyanate and niaziminin. It helps maintains the blood pressure so, good for cardiovascular health.

3.Improve haemoglobin level: Moringa extract contains iron and folate so helps in treating anaemia and sickle cell disease. It also helps the body to absorb iron, so help increasing the red cell count.

4.Medicinal: Moringa extract has been found to heal wounds. Since it has anti-bacterial, anti-viral and anti-inflammatory properties, it has been found to fight against bacterial diseases, gastritis, ulcerative colitis. It has shown to improve lung function so helps in asthma. Since, it improves the haemoglobin level, reduces blood glucose so helps to treat diabetes.

5.Wellbeing: Due to its antioxidant properties, releases the toxicity from the kidneys so contribute to kidney health. Improves eyesight by dilating the retinal vessels, preventing retinal dysfunction. Due to its richness in calcium and phosphorous, it contributes to bone health. It also found to help in mood disorders, depression and anxiety. It has anti-cancer properties. It also prevents liver damage.

Risks :

Before, taking any supplements, it is important to inform and discuss with your physician. Many people are on regular medication for hypertension, diabetes or antidepressants, so there may be chances of drug interference when taken along moringa extract.

Before, buying the supplement, it important to read the labels for any kind of additives and the quantity to be used.

It has anti infertility properties so contraindicated for pregnancy.